Klinische Molekulargenetik und Epigenetik

Klinische Molekulargenetik und Epigenetik

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Research Highlights


Uncovering the gastrointestinal passage, intestinal epithelial cellular uptake, and AGO2 loading of milk miRNAs in neonates using xenomiRs as tracers.

Weil PP, Reincke S, Hirsch CA, Giachero F, Aydin M, Scholz J, Jönsson F, Hagedorn C, Nguyen DN, Thymann T, Pembaur A, Orth V, Wünsche V, Jiang PP, Wirth S, Jenke ACW, Sangild PT, Kreppel F, Postberg J.

Am J Clin Nutr. 2023 Mar 22:S0002-9165(23)46299-5. doi: 10.1016/j.ajcnut.2023.03.016. Online ahead of print.

PMID: 36963568


An Adenoviral Vector as a Versatile Tool for Delivery and Expression of miRNAs.

Scholz J, Weil PP, Pembaur D, Koukou G, Aydin M, Hauert D, Postberg J, Kreppel F, Hagedorn C.

Viruses. 2022 Sep 2;14(9):1952. doi: 10.3390/v14091952.

PMID: 36146759 Free PMC article.


β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor.

Weil P, van den Bruck R, Ziegenhals T, Juranek S, Goedde D, Orth V, Wirth S, Jenke AC, Postberg J.

Gut. 2020 Jul;69(7):1359-1361. doi: 10.1136/gutjnl-2019-319015. Epub 2019 Jun 14.

PMID: 31201286 Free PMC article. No abstract available.


Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx.

Hensel KO, Cantner F, Bangert F, Wirth S, Postberg J.

Epigenetics Chromatin. 2018 Jun 22;11(1):34. doi: 10.1186/s13072-018-0204-2.

PMID: 29933745 Free PMC article.


27nt-RNAs guide histone variant deposition via 'RNA-induced DNA replication interference' and thus transmit parental genome partitioning in Stylonychia.

Postberg J, Jönsson F, Weil PP, Bulic A, Juranek SA, Lipps HJ.

Epigenetics Chromatin. 2018 Jun 12;11(1):31. doi: 10.1186/s13072-018-0201-5.

PMID: 29895326 Free PMC article.


Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse model.

Chao CM, van den Bruck R, Lork S, Merkle J, Krampen L, Weil PP, Aydin M, Bellusci S, Jenke AC, Postberg J.

Clin Epigenetics. 2018 Mar 20;10:37. doi: 10.1186/s13148-018-0469-0. eCollection 2018.

PMID: 29581793 Free PMC article.


Virus-host interplay in hepatitis B virus infection and epigenetic treatment strategies.

Hensel KO, Rendon JC, Navas MC, Rots MG, Postberg J.

FEBS J. 2017 Nov;284(21):3550-3572. doi: 10.1111/febs.14094. Epub 2017 May 19.

PMID: 28457020 Review.